Paracap

Paracap Paracetamol 500mg 50x10s

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Paracap Paracetamol 500mg 50x10s
Paracap Paracetamol 500mg 50x10s
Paracap Paracetamol 500mg 50x10s

Paracap

Paracap Paracetamol 500mg 50x10s

20 reviews Sold: 154

Original price was: RM235.00.Current price is: RM200.90. -15%

Availability: 89 in stock

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Quantity

Availability: 89 in stock

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Product Details
Product Registration / Notification
MAL20014030X
Product Description

Action

Pharmacology: Pharmacodynamics: Paracetamol is a centrally acting analgesic and antipyretic with minimal anti-iflammatory properties.
Analgesic: The mechanism of analgesic action has not been fully determined. Paracetamol may act predominantly by inhibiting prostaglandin synthesis in the central nervous system (specifically cyclooxygenase (COX)-2) and, to a lesser extent, through a peripheral action by blocking pain-impulse generation.

The peripheral action may also be due to inhibition of prostaglandin synthesis or to inhibition of the synthesis or actions of other substances that sensitize pain receptors to mechanical or chemical stimulation.
Antipyretic:

Paracetamol act centrally on the hypothalamic heat-regulating center to produce peripheral vasodilation resulting in increase blood flow through the skin, sweating and heat loss. Paracetamol reduces fever by inhibiting the formulation and release of prostaglandins in the CNS and by inhibiting endogenous pyrogens at the hypothalamic thermoregulator center.
Pharmacokinetics:

 Following oral administration paracetamol is rapidly absorbed.
Paracetamol absorption takes place mainly in the small intestine and therefore the rate of absorption is depending on the rate of gastric emptying. It has been shown that drugs which delay gastric emptying also delay the absorption of paracetamol whereas metoclopramide (a drug which increases the rate of gastric emptying) accelerates absorption of the analgesic through the total amount absorbed doses not increase.
The presence of food in the stomach has also been reported to reduce the rate of absorption of paracetamol. Alterations in gastric pH have no appreciable effect on paracetamol absorption. During absorption, the amount of paracetamol which is inactivated is negligible and it has been shown that pracetamol does not affect gastric mucosal permeability and does not produce mucosal bleeding.
Peak plasma concentrations are reached 1 hour after absorption. The plasma half life is 1 to 3 hours.
Paracetamol penetrates the brain and is present in breast milk of human.
Paracetamol is metabolized by the microsomal enzyme system of the liver. This metabolism is mainly to the glucuronide and sulphate conjugates, accounting for approximately 49% and 26% of the ingested dose respectively. About 4% is excreted as free paracetamol. Other minor pathways include the production of cathecol derivatives and cysteine conjugates (via glutathione). Paracetamol excretion is rapid and occurs via the urine.

Indications/Uses

For relief of fever and pain.

Dosage/Direction for Use

For children aged 1 to 6 years. Give in 6 hourly intervals; not more than 4 times a day. (See Table 1.)

SKU
53711
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Reviews

4.8 out of 5 stars

20 reviews

4.8

Overall

5
16
4
4
3
0
2
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1
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What others are saying

  1. Valerie Chai

    Terima kasih..brg disampai dlm keadaan baik

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  2. Ganesh

    Good packaging. Good product. Confirmed original!

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  3. Santosh S.

    Original product, well packed and clean. Impressive Alpro

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  4. fathen55

    Restock it for family, able to relieve fever and headache

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  5. Che Azril

    Good product quality. Recommended Alpro. Good packaging

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  6. Zoe

    Received in good condition ..product is ok with this price….confirm is original product…2nd time bUy here.TQ Alpro

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  7. Isaac Lee

    Helps in relieving mild headache and fever effectively

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  8. Theam Jia Hui

    Terima kasih barang sampai dengan cepat Dan dalam situasi yang bagus.

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  9. chiti

    Thanks Alpro….product received in good condition

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  10. Stevie

    Nicely packed in blister, no damage

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  11. Jessica

    Terima kasih Alpro barang sampai dalam keadaan yang baik dan saya sangat memuaskan.

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  12. Siaw Hui

    Very secure packaging, my favorite product!!

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  13. Yung Cheon

    Blister were in good condition

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  14. Ya Nee

    Cepat smpai. Hrga pun brbaloi sgt. Smua barang smpai dgn selamat dan xda masalah.

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  15. Jezreel

    Fast delivery, very secure packaging..will repeat another soon

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  16. Liana

    Helps in relieving fever, always have a stip in my bag

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  17. Sophia

    Very good Alpro. So nice. Items were received in good condition.

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  18. Rahman

    Terima barang dalam keadaan sempurna harga yang berpatutan, tq Alpro…

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  19. Sira

    Good for relieving mild headache

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  20. Sui En

    Barang dah sampai, cepat Alpro buat penghantaran

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