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On-and-Off Fever in Babies: When to Worry & What to Do

By Alpro Pharmacy

February 12, 2025

Fever is one of the most common concerns among parents, especially when their baby experiences recurrent or on-and-off fever. It is distressing to see your little one feeling unwell, and many parents worry whether it indicates a serious health problem. However, fever itself is not an illness but a natural defense mechanism of the body against infections and other underlying conditions. So, why does fever keep coming back, and how should parents manage it?

What Is Considered a Fever?

A baby is considered to have a fever if their temperature reaches:

  • ≥ 38°C (100.4°F) (rectal or ear measurement)
  • ≥ 37.8°C (100°F) (oral measurement)
  • ≥ 37.5°C (99.5°F) (axillary/armpit measurement)

Fevers are typically categorized into: 
✅ Low-grade fever: 37.5°C – 38.4°C (99.5°F – 101°F) – Usually mild and does not require immediate intervention. 
❗ Moderate fever: 38.5°C – 39.4°C (101.3°F – 103°F) – Can cause discomfort but often manageable at home. 
⚠️ High fever: 39.5°C (103.1°F) or above – Requires medical attention, especially if persistent.

Why Does My Baby Have Recurrent Fever?

Several factors can cause a baby to have fever that comes and goes:

a) Viral Infections (Most Common Cause)

Viruses account for 80-90% of fevers in babies. Common viral illnesses that cause on-and-off fever include:

  • Common colds (Rhinovirus)
  • Flu (Influenza)
  • Roseola (sudden high fever lasting 3-5 days, followed by a rash)
  • Hand, Foot, and Mouth Disease (HFMD)
  • Respiratory Syncytial Virus (RSV)

Viral fevers usually last 3-5 days and resolve on their own.

b) Bacterial Infections

Unlike viral infections, bacterial infections may require antibiotics. Examples include:

  • Ear infections (Otitis Media)
  • Urinary tract infections (UTIs)
  • Pneumonia
  • Bacterial throat infections (Strep throat)
  • Meningitis (rare but serious)

A bacterial fever may persist longer, be higher in temperature, and return if untreated.

c) Post-Vaccination Fever

It is normal for babies to develop a mild fever (below 38.5°C) 24-48 hours after vaccinations like DTaP, MMR, or pneumococcal vaccines. This is a sign that the body is building immunity. Fever should not last beyond 48 hours.

d) Teething Fever: A Myth

Contrary to popular belief, teething does not cause high fever. Mild temperature elevation (< 38°C) is possible due to gum inflammation, but persistent or high fever is not from teething alone.

e) Environmental Factors

  • Overdressing or hot weather can cause heat-related fevers.
  • Dehydration can lead to mild fever and irritability.

f) Underlying Health Conditions

If a baby frequently experiences fever without an obvious cause, underlying conditions such as autoimmune disorders, periodic fever syndromes, or immunodeficiencies may need to be ruled out by a doctor.

Specific Management Strategies

A. Medication Management

  • Paracetamol (Acetaminophen):
    • Dosage: 15 mg/kg per dose every 4-6 hours, up to a maximum of 4 doses per day.
    • Use in infants >2 months old.
    • Available in liquid form; ensure accurate dosing using a syringe, not a spoon.
  • Ibuprofen:
    • Dosage: 10 mg/kg per dose every 6-8 hours.
    • Use only in infants >6 months old.
    • Avoid ibuprofen in dehydrated or febrile infants with possible kidney issues.

B. Hydration Management

Maintaining hydration is essential, as fever increases fluid loss. Specific recommendations include:

  • For infants <6 months:
    • Continue breastfeeding or formula feeding on demand (every 2-3 hours).
    • If the baby refuses to feed, offer smaller, more frequent feedings.
    • Avoid plain water, as it can cause electrolyte imbalances.
  • For infants >6 months:
    • Continue milk feeds and introduce oral rehydration solutions (ORS) like Pedialyte if signs of dehydration occur (e.g., dry lips, decreased urine output).
    • Offer small spoonfuls (5-10 ml) of ORS every 5-10 minutes.
    • Avoid sugary drinks, sodas, or fruit juices, as they may worsen dehydration.

C. Temperature Control and Comfort Measures

  • Dress the baby in light, breathable clothing and keep the room at a comfortable temperature (21-23°C or 70-74°F).
  • Lukewarm sponge baths can help bring down fever (avoid cold water or alcohol rubs, which may cause shivering and worsen discomfort).
  • Encourage rest and sleep, but do not force sleep if the baby is irritable.

Should I Worry About Febrile Seizures?

Some babies (typically between 6 months – 5 years old) may develop febrile seizures when fever spikes rapidly. While terrifying to witness, febrile seizures are usually harmless and do not cause brain damage. If a seizure occurs: 
✅ Stay calm and lay the baby on their side. 
✅ Do not put anything in their mouth. 
✅ Time the seizure – If it lasts >5 minutes, seek emergency care.

How Can Parents Prevent Frequent Fevers?

While fever itself cannot always be prevented, you can reduce the risk: 

  • Practice good hygiene – Wash hands frequently, especially before feeding. 
  • Stay up to date with vaccinations – Helps protect against serious infections. 
  • Ensure proper nutrition – Strengthens the immune system. 
  • Avoid crowded places during flu season – Reduces exposure to viruses.

Conclusion: When in Doubt, Consult a Pediatrician or a Pharmacist

Recurrent fever in babies is often caused by common viral infections and usually resolves within 3-5 days. However, if fever is persistent, high, or accompanied by worrying symptoms, it’s best to seek medical advice.

💡 If you are concerned about your baby’s fever, visit your nearby pediatrician or Alpro Pharmacy for expert guidance.

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If you have any health-related questions, you can consult our medical professionals at MamaBe Expert Group. Our pharmacists are ready to assist you.

Disclaimer: Regardless of the date of the content on the website, no content is a substitute for direct medical advice from a qualified healthcare professional.

Citations

  • American Academy of Pediatrics. (2021). Fever and your baby: When to worry. Retrieved from https://www.healthychildren.org
  • Chiappini, E., Venturini, E., Remaschi, G., et al. (2017). Update of the 2009 Italian Pediatric Society Guidelines for Management of Fever in Children. BMC Pediatrics, 17, 210. https://doi.org/10.1186/s12887-017-0951-7
  • Sullivan, J. E., & Farrar, H. C. (2011). Fever and antipyretic use in children. Pediatrics, 127(3), 580-587. https://doi.org/10.1542/peds.2010-3852
  • World Health Organization. (2023). Managing fever in young children. Retrieved from https://www.who.int
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