Higher Blood Glucose Leads to Higher Serum Uric Acid?

health

Higher Blood Glucose Leads to Higher Serum Uric Acid?

By Alpro Pharmacy

July 12, 2023

Many have this perception that serum uric acid is only important when you have a gout attack or you eat too much seafood.

In this article, let’s explore the relationship between blood glucose and serum uric acid.

What is Blood Glucose?

Blood glucose, also known as blood sugar, refers to the amount of sugar (glucose) present in the bloodstream. It serves as a primary source of energy for our body’s cells, and its regulation is essential for overall health.

The hormone insulin, produced by the pancreas, helps regulate blood glucose levels by directing the muscle and fat cells to take in glucose.

What is Serum Uric Acid?

Serum uric acid is a waste product that results from the breakdown of purines, which are naturally existing substances found in certain foods and also produced by our body.

Normally, uric acid dissolves in the blood and passes through the kidneys to be excreted in urine. However, elevated levels of serum uric acid can lead to a condition known as hyperuricemia, which is associated with various health issues, such as gout & kidney stone.

Elevated Blood Glucose Imposed Risk in Developing Hyperuricemia

Research suggests that there is a correlation between blood glucose and serum uric acid levels. Individuals with elevated blood glucose, such as those with diabetes or prediabetes, may have an increased risk of developing hyperuricemia.

Conversely, studies have also shown that individuals with hyperuricemia may be at a higher risk of developing altered glucose metabolism or type 2 diabetes.

Mechanisms behind the Relationship

The exact mechanisms behind the relationship between blood glucose and serum uric acid are still being investigated. However, there are several theories that help explain this connection:

Insulin Resistance

Insulin resistance, a hallmark of type 2 diabetes, may contribute to increased serum uric acid levels. Insulin resistance interferes with the body’s ability to utilize glucose properly, leading to higher blood glucose levels. It may also affect the kidneys’ ability to excrete uric acid efficiently, resulting in elevated serum uric acid levels. Conversely, a 2016 study reports that uric acid build up can lead to worsen insulin resistance.

Purine Metabolism

Elevated blood glucose levels from fructose, a major component of added sugar, can increase the breakdown of purines, leading to higher production of uric acid. Additionally, insulin resistance may disrupt purine metabolism, further contributing to increased uric acid levels.

Maintaining Balance

To maintain a healthy balance between blood glucose and serum uric acid, it is essential to focus on lifestyle modifications and, in some cases, medical interventions.

Healthy Diet

Adopting a well-balanced diet that includes whole grains, lean proteins, fruits and vegetables, can help regulate blood glucose and serum uric acid levels. Limiting the consumption of purine-rich foods, such as organ meats, seafood, and sugary beverages, is beneficial.

Regular Physical Activity

Engaging in regular exercise can improve insulin sensitivity, promote weight management, and help regulate blood glucose levels. It can also contribute to overall metabolic health and aid in managing serum uric acid levels.

Medication

In certain cases, healthcare professionals may prescribe medications to manage blood glucose or serum uric acid levels. It is important to consult with a healthcare provider to determine the most appropriate treatment options for you.

Check Your Serum Uric Acid Today at Alpro Pharmacy

Remember, taking preventative care of your health today can have a positive impact on your well-being in the long run. Health screening is essential to help identify red flags at an earlier stage.